Friday, 31 August 2018

Function of liver in digestive system

What is the liver? Describes the function of liver in digestion.

The liver, the largest organ in the mammalian body, that lies just under the diaphragm.
In the liver, millions of cells that is called hepatocytes take up nutrients that absorbed from the intestines and release them into the bloodstream. Hepatocytes perform the function the manufacture of blood proteins prothrombin and albumin.

Some major metabolic functions of the liver are given below:

1. Removal of amino acids from organic compounds.
2. Urea formation from proteins and conversion of excess amino acids into urea to decrease body levels of ammonia.
3. Manufacture of most of the plasma proteins, formation of fetal erythrocytes, destruction of worn-out erythrocytes, and synthesis of the blood-clotting agents prothrombin and fibrinogen from amino acids.
4. Synthesis of nonessential amino acids.
5. Conversion of galactose and fructose to glucose.
6. Oxidation of fatty acids.
7. Formation of lipoproteins, cholesterol, and phospholipids.
8. Conversion of carbohydrates and proteins into fat.
9. Modification of waste products, toxic drugs, and poisons.
10. Synthesis of vitamin A from carotene, and with the kidneys,
participation in the activation of vitamin D.
11. Maintenance of a stable body temperature by raising the temperature of the blood passing through it. Its many metabolic activities make the liver the major heat producer in a mammal’s body.
12. Manufacture of bile salts, which are used in the small intestine for the emulsification and absorption of simple fats, cholesterol, phospholipids, and lipoproteins.
13. Main storage center. The liver stores glucose in the form of glycogen, and with the help of insulin and enzymes, converts glycogen back into glucose as the body needs it.

 The liver also stores fat-soluble vitamins (A, D, E, and K), and minerals, such as iron, from the diet. The liver can also store fats and amino acids, and convert them into usable glucose as required.


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